Serotonin in allergic rhinitis: a possible role for behavioural symptoms.

نویسندگان

  • Giorgio Ciprandi
  • Mara De Amici
  • Mariangela Tosca
  • Roberta Alesina
  • Gianluigi Marseglia
  • Dietmar Fuchs
چکیده

Allergic rhinitis (AR) is a very frequent disease which is not only characterized by nasal symptoms, but also with behavioural changes. This study evaluated the serum serotonin levels in patients with pollen-induced AR during and outside the pollen season.One-hundred-two (56 females, 46 males, median age: 28.7 years) were included in this study: 56 with seasonal AR (SAR) evaluated outside the pollen season and so without allergic inflammation and symptoms, and 46 with SAR evaluated during the pollen season with symptoms. Blood specimens were collected to assess serum concentrations of serotonin and to compare results to scores of a Quality of Life (QoL) questionnaire which was performed in all subjects. Serotonin serum concentrations were higher in AR patients out of pollen season than in (p<0.01). There was a very strong direct relationship between QoL and serotonin concentrations.This preliminary study demonstrates that SAR influences serotonin concentrations and that serum serotonin could serve as a biomarker in AR patients with behavioural symptoms.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Investigating the frequency of adenoid hypertrophy and allergic rhinitis in children with mouth breathing complaints

Background and Objectives: Nocturnal snoring and open mouth breathing in children is one of the common causes of referrals to pediatricians. The two most common reasons of this problem are adenotonsillar hypertrophy and allergic rhinitis. Based on the findings, there is still no significant relationship between these two diseases. Therefore, the aim of this study was to determine the frequency ...

متن کامل

Oral Administration of Zataria multiflora Extract Decreases IL-17 Expression in Perennial Allergic Rhinitis

Background: Rhinitis, which occurs most commonly as allergic rhinitis and affects 20% of the world&rsquo;s population, is a major health care burden causing significant morbidity. Considering the high prevalence of allergic rhinitis and anti-inflammatory effects of thyme, a favorite condiment, we performed a randomized clinical trial to determine whether thyme can relieve allergic rhinitis symp...

متن کامل

Survey on the Prevalence of Allergic Rhinitis and its Effect on the Quality of High School Students’ Life

Introduction: Allergic rhinitis (AR) is a common airway disease. In order to study  the  prevalence of  AR in high school students  in  Kerman, the Score for Allergic Rhinitis (SFAR) was used and the quality of life  in  the  students  affected  by  rhinitis was  evaluated using the SF-36 questionnaire.   Materials and Methods: This was a cross-sectional, analytical, descriptive study, based o...

متن کامل

Effect of Botulinum Neurotoxin A Injection into the Submucoperichondrium of the Nasal Septum in Reducing Idiopathic Non-Allergic Rhinitis and Persistent Allergic Rhinitis

Introduction: Submucoperichondrial injection of botulinum neurotoxin A (BTA) in the nasal septum is a promising therapeutic option in the treatment of persistent allergic rhinitis (AR) and non-allergic rhinitis, and is safer and more effective than intraturbinate injection in reducing clinical symptoms.   Materials and Methods: Forty patients diagnosed with persistent AR or non-allergic rhiniti...

متن کامل

Survey on the Prevalence of Allergic Rhinitis in Junior High School Students in Isfahan, Iran

Background Allergic rhinitis (AR) is a common form of nose inflammatory disease that occurs when the mucosal immune system overreacts to environmental allergens especially in the air. It’s absolutely clear that the prevalence of AR varies between different countries, and even between the various areas of a country. The purpose of present investigation is to determine the prevalence of AR, as mo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Iranian journal of allergy, asthma, and immunology

دوره 10 3  شماره 

صفحات  -

تاریخ انتشار 2011